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Patients who are in the last phase of life due to advanced diseases or old-age frailty often face difficult decisions: Quantitative Research Assignment, RCSI, Ireland

University Royal College of Surgeons (RCSI)
Subject Quantitative Research

Patients who are in the last phase of life due to advanced diseases or old-age frailty often face difficult decisions about potentially life-prolonging treatment. Patients are considered to be in the last phase of life when they have a life-threatening progressive illness, have a limited life expectancy, or have a diagnosis of old-age-related frailty.

Decisions about potentially life-prolonging treatment concerns for instance starting, refraining, or withdrawing from chemotherapy, radiotherapy, surgery, intravenous administration of antibiotics, or artificial nutrition. Such treatments may have limited benefits besides prolonging life. However, they may have harmful side effects such as nausea, fatigue, or restrictions of movement, and therefore might harm the patient’s quality of life.

In these specific situations, difficult trade-offs can be at stake: on the one hand offering a treatment that might result in prolongation of life but could also have harmful side effects that might reduce the quality of life, or on the other hand, refraining from or withdrawing treatment and focusing on the quality of life.

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