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Alzheimer’s disease is the most common form of dementia, accounting for nearly 60 to 80% of all cases. It is a slowly progressive and irreversible: Healthcare Assignment, OC, Ireland

University The Open College (OC)
Subject Healthcare

Alzheimer’s disease is the most common form of dementia, accounting for nearly 60 to 80% of all cases. It is a slowly progressive and irreversible neurodegenerative disease that affects cognition, behavior, and normal function. AD is identified by neuritic plaques and neurofibrillary tangles resulting from amyloid-beta peptides (Aβ) accumulation in the most affected region of the brain, the medial temporal lobe, and neocortical structures.

Emil Kraepelin is the first to call this mental condition Alzheimer’s disease in his 8th edition psychiatry handbook. Progressive loss of neuropsychological functions can be a result of cerebral disorder or other factors such as infections, intoxications, or an anomaly in the circulatory and pulmonary systems, which can cause a reduction in the flow of oxygen supply to the brain, nutritional and vitamin B12 deficiencies, cancerous growth, infections. AD typically manifests through a progressive loss of episodic memory and cognitive function, with later deficiency of language and visuospatial abilities. Such changes are often accompanied by behavioral disorders such as apathy, aggressiveness, and depression.

There is currently no cure for Alzheimer’s disease, although there are medications that just help to treat the symptoms. The initial manifestation of AD is seen through a progressive loss of episodic memory function, which later leads to loss of language, comprehension, and visuospatial functions, these changes are usually associated with behavioral disorders such as depression, apathy, aggressiveness and progressively unpleasant symptoms, such as disorientation, developing uncertainty about events, location, and time; inability to recognize family, friends, and professional caregivers; severe memory loss; and difficulties in performing activities of daily living like bathing, eating, speaking, walking, etc.

The popular threatening factor is aging, and it normally affects people of the age of 65 years and above. The cause of AD is not well understood and about 70% of the disease incidence is attributed to genetics. Other risk factors are aging, untreated clinical depression, family history, and lifestyle.

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